Ozempic, and drugs like it, are powerful, versatile, and have made a huge difference in people’s lives. But bigger, better, beefier spins on the Ozempic approach are on the horizon. So let’s take a lo
4:05 This is the stuff that, as a pharmacy tech, I love to learn about and then share with my friends and family, who are kind enough to humor my drug rants lol.
My favorite part of GLP-1 lore is how they came about. I'm oversimplifying by far, but basically one mad scientist looked at the gila monster and how infrequently they need to eat and thought "hey, that would be pretty cool!" His research inspired a couple of other researchers to develop exenatide (probably better known by its brand name Byetta), the synthetic version of exendin-4, a hormone in gila monster venom.
On drug names, I used to work in research pharmacy and let me say, I'd much rather memorize the long chemical names than keep referring to drugs by the alphanumeric designations they're given early on. At least the chemical names follow some kind of logic while the IP identifiers look like a toddler had a field day with the letter/number magnets on the fridge.
my sister had a traumatic brain injury that affected her hunger/craving signals. basically they never turned off. zepbound has been very effective in treating that for her.
as a type 1 diabetic, my emergency hypoglycemia treatment is a glucagon injection. (in T1D it doesn't stimulate insulin production is because those cells no longer exist/work, it just convinces fat cells to release stored energy as glucose.) it's very interesting to hear that it may have additional uses to benefit more people.
My weight issues didn't come from overeating. Before I had kids, I did triathlons for fun. I gained the recommended or less than the recommended amount of weight with each pregnancy. The problem was, my body never got rid of it again. Alter nursing, my body was prepared to feed an entire village of infants, and then afterwards, it decided to hang on to the weight just in case of famine. Then I gained another 10 lb during covid, like a lot of people. 85 extra pounds is a lot when you're only 5'3. I'm doing a clinical trial for a medication like one of the ones named in the video. It allowed me to get the drug for free when I couldn't afford it before. I've lost over 25% of my body weight, and I feel more alert, energetic, physically able, and healthy than I have in 18 years. Now I know that I never would have lost the weight without help, because of the way my body's insulin receptors handle sugars. It hasn't been easy, but I'm glad I did it. I also now go to the gym 4 days a week, because I have enough energy again.
On reta. It's absolutely a lifechanging medication and I can't wait until it's on the market and available for compounding. Over 100lbs down and counting.
We've already tried a cannabinoid receptor antagonist. It was called rimonabant and it resulted in suicides because it DESTROYED the reward pathways. Set off a whole lot of lawsuits. I think it'd be better to just leave our reward pathways alone overall. 😬
As someone with gastroparisis it helped me get diagnosed because it showed my symptoms more than just when I was not on it. It helped me lose weight but for the wrong reason. I already had a paralyzed stomach when I started it, as someone with eds it actually is a great help if I didn't have gastroparisis because my body isn't very good at using its hormones properly.
This video actually reminded me I was a day late on my tirzepatide dose lol. So thank you for that.
I originally ended up diving into the research about GLP-1s when my mom was advised to start taking it, maybe about four months before I was (by two different doctors in two different practices mind you, not some conspiracy or something). Both of us were advised due to risk of type 2 diabetes. I was rather impressed just how robust the research into GLP-1s was since it was originally formulated with therapeutic treatments of diabetes and heart conditions in mind, even though it's popularity in recency is weight loss.
Still not the biggest fan of having to take it admittedly. I prefer to limit my use of medications, it concerns me whenever I research something that I end up drowning in discussions from the more weight loss fad side of the medical world and how people really build their mental health around their body weight, and I genuinely find it frustrating how my doctors all act like it'll be a panacea for my other conditions (I was diagnosed with mild sleep apnea and the doctor insisted that he usually didn't prescribe a CPAP for mild cases but would in my case because I was ov
I have been on tirzepatide for one month and it has been life changing. I feel better than ever. Never want to go back. Inflammation is down, not constantly thinking about food, etc.
my dumbass read that as the sequels to the odyssey, i was really excited to hear about what science says about the Aeneid
We use cookies, device fingerprinting and cross-device tracking to personalise content, serve targeted advertising, and analyse how you use our site across your devices. By clicking Accept all you consent to the use of these tracking technologies. Your data may be used to build a profile of your interests and show you personalised ads on other sites.
Privacy policy
Comments (20)
Daily Junction discussion mixed with clearly attributed comments from the original video provider.
Join in — free. Comments on Daily Junction are for members, so real names stay rare and bots stay out.
One field. We email you a 6-digit code — no password needed. Your comment is kept while you do it.
Under 13? You’ll need a parent’s OK first — it takes them one click.
My favorite part of GLP-1 lore is how they came about. I'm oversimplifying by far, but basically one mad scientist looked at the gila monster and how infrequently they need to eat and thought "hey, that would be pretty cool!" His research inspired a couple of other researchers to develop exenatide (probably better known by its brand name Byetta), the synthetic version of exendin-4, a hormone in gila monster venom.
On drug names, I used to work in research pharmacy and let me say, I'd much rather memorize the long chemical names than keep referring to drugs by the alphanumeric designations they're given early on. At least the chemical names follow some kind of logic while the IP identifiers look like a toddler had a field day with the letter/number magnets on the fridge.
Okay, done with my drug rants. Sorry. 😅
as a type 1 diabetic, my emergency hypoglycemia treatment is a glucagon injection. (in T1D it doesn't stimulate insulin production is because those cells no longer exist/work, it just convinces fat cells to release stored energy as glucose.) it's very interesting to hear that it may have additional uses to benefit more people.
These drugs are life changing.
I originally ended up diving into the research about GLP-1s when my mom was advised to start taking it, maybe about four months before I was (by two different doctors in two different practices mind you, not some conspiracy or something). Both of us were advised due to risk of type 2 diabetes. I was rather impressed just how robust the research into GLP-1s was since it was originally formulated with therapeutic treatments of diabetes and heart conditions in mind, even though it's popularity in recency is weight loss.
Still not the biggest fan of having to take it admittedly. I prefer to limit my use of medications, it concerns me whenever I research something that I end up drowning in discussions from the more weight loss fad side of the medical world and how people really build their mental health around their body weight, and I genuinely find it frustrating how my doctors all act like it'll be a panacea for my other conditions (I was diagnosed with mild sleep apnea and the doctor insisted that he usually didn't prescribe a CPAP for mild cases but would in my case because I was ov